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453 Schizophrenia Astrocytic changes in schizophrenia are rather mild

Ferrs-I-Tortajada J, Berbel-Tornero O, Garcia-I-Castell J, Lpez-Andreu JA, Sobrino-Najul E, Ortega-Garca JA

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Therefore, this review article focussed on the potential of nano-engineering in stem cells as a therapeutic approach for MS, focusing on the synergistic effects of combining stem cell biology with nanotechnology to stimulate the proliferation of oligodendrocytes (OLs) from neural stem cells and OL precursor cells, by manipulating neural signalling pathways-PDGF, BMP, Wnt, Notch and their essential genes such as Sox, bHLH, Nkx